Research

For more than 40 years, my work has focused
on a simple but profound question:
For more than 40 years, my work has focused on a simple but profound question:

Why do psychological symptoms feel so powerful — even when we consciously know better?

Through clinical observation, brain imaging research, and experimental studies, I developed what is now called Dual-Brain Psychology (DBP) — a model suggesting that the two hemispheres of the brain can represent different emotional “selves.” In many people, one hemisphere may carry unresolved early trauma, fear, or emotional pain, while the other carries a more mature, resilient perspective.

blue and white abstract painting

This helps explain why someone may know they are safe — yet still feel panic.

Why someone may want to stop drinking — yet feel compelled to continue. Why depression can feel like a separate force inside the mind.

Over the years, this model has been explored through:

  • Clinical case studies

  • Brain imaging (fMRI) research

  • Studies of lateralized visual stimulation

  • Development of hemispheric-based therapeutic tools

  • Ongoing research into noninvasive brain stimulation

More recently, my research has expanded into broader questions about how experience itself affects the brain — and whether meaning and subjectivity may play a more active role in biology than traditionally recognized.

This work bridges psychiatry, neuroscience, and emerging ideas about how the brain generates lived experience.

The articles linked below represent both clinical findings and theoretical explorations. Some are directly applicable to treatment. Others address deeper scientific questions about consciousness, memory, trauma, and the nature of experience.

Together, they reflect a lifetime of research driven by one goal:

To understand how the mind heals — and how suffering can be transformed.

SOME SELECTED ARTICLES

September, 2025

A four-field quantum model of life, subjectivity, consciousness, and memory: integrating dual-brain psychology and biophoton quantum interactions

April, 2008

Prediction of Clinical Outcomes From rTMS in Depressed Patients With Lateral Visual Field Stimulation: A Replication

January, 2021

Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: A clinical overview and case series

June, 2022

Individual Differences in Hemispheric Emotional Valence by Computerized Test Correlate with Lateralized Differences in Nucleus Accumbens, Hippocampal and Amygdala Volumes

March, 2007

Determination of hemispheric emotional valence in individual subjects: A new approach with research and therapeutic implications

June, 2021

A Dual Mind Approach to Understanding the Conscious Self and Its Treatment

October, 2022

Dual-Brain Psychology: A novel theory and treatment based on cerebral laterality and psychopathology

October, 2008

Can the Different Cerebral Hemispheres Have Distinct Personalities?

August, 2020

A Novel Treatment of Opioid Cravings With an Effect Size of .73 for Unilateral Transcranial Photobiomodulation Over Sham

SOME SELECTED ARTICLES

September, 2025

A four-field quantum model of life, subjectivity, consciousness, and memory: integrating dual-brain psychology and biophoton quantum interactions

April, 2008

Prediction of Clinical Outcomes From rTMS in Depressed Patients With Lateral Visual Field Stimulation: A Replication

January, 2021

Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: A clinical overview and case series

June, 2022

Individual Differences in Hemispheric Emotional Valence by Computerized Test Correlate with Lateralized Differences in Nucleus Accumbens, Hippocampal and Amygdala Volumes

March, 2007

Determination of hemispheric emotional valence in individual subjects: A new approach with research and therapeutic implications

June, 2021

A Dual Mind Approach to Understanding the Conscious Self and Its Treatment

October, 2022

Dual-Brain Psychology: A novel theory and treatment based on cerebral laterality and psychopathology

October, 2008

Can the Different Cerebral Hemispheres Have Distinct Personalities?

August, 2020

A Novel Treatment of Opioid Cravings With an Effect Size of .73 for Unilateral Transcranial Photobiomodulation Over Sham

SOME SELECTED ARTICLES

September, 2025

A four-field quantum model of life, subjectivity, consciousness, and memory: integrating dual-brain psychology and biophoton quantum interactions

June, 2021

A Dual Mind Approach to Understanding the Conscious Self and Its Treatment

April, 2008

Prediction of Clinical Outcomes From rTMS in Depressed Patients With Lateral Visual Field Stimulation: A Replication

October, 2022

Dual-Brain Psychology: A novel theory and treatment based on cerebral laterality and psychopathology

January, 2021

Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: A clinical overview and case series

October, 2008

Can the Different Cerebral Hemispheres Have Distinct Personalities?

June, 2022

Individual Differences in Hemispheric Emotional Valence by Computerized Test Correlate with Lateralized Differences in Nucleus Accumbens, Hippocampal and Amygdala Volumes

August, 2020

A Novel Treatment of Opioid Cravings With an Effect Size of .73 for Unilateral Transcranial Photobiomodulation Over Sham

March, 2007

Determination of hemispheric emotional valence in individual subjects: A new approach with research and therapeutic implications

Research and Ongoing Work

Scientific breakthroughs

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Fredric Schiffer, MD

30 Lincoln St, Newton Highlands, MA 02461

+1 (781) 405-8800

fred.schiffermed@gmail.com

Copyright © 2025 Fredric Schiffer, MD. All Rights Reserved.

Copyright © 2025 Fredric Schiffer, MD.
All Rights Reserved.